A vertebral body compression fracture associated with osteoporosis, trauma, or cancer can lead to excruciating and intractable localized back pain and height reduction. The pain resulting from the fracture and subsequent loss of mobility can lead to multiple medical problems, partly related to pain medication and immobilization. Certain vertebral fractures, that require enhanched structural support, may benefit from the use of intravertebral implants. Two small needles are introduced into the compressed vertebral body through small incisions in the skin. Intravertebral implants, with controlled self-expansion capacity, are introduced within the fractured vertebra and progressively expanded. Bone cement is then injected through the same needles to properly bond the vertebra and the implants. In most patients this leads to significant pain relief and significant spinal structural stabilization. In spinal metastases the implants can provide mechanical support, even to those vertebral body markedly eroded by aggressive tumor lesions. The majority of patients go home the same day.